Tofacitinib for polyarteritis nodosa: a tailored therapy

Ann Rheum Dis. 2016 Dec;75(12):2214-2216. doi: 10.1136/annrheumdis-2016-209330. Epub 2016 Aug 24.
No abstract available

Keywords: Cytokines; Systemic vasculitis; Treatment.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Biopsy, Needle
  • Computed Tomography Angiography / methods
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Male
  • Molecular Targeted Therapy
  • Piperidines / therapeutic use*
  • Polyarteritis Nodosa / diagnostic imaging
  • Polyarteritis Nodosa / drug therapy*
  • Polyarteritis Nodosa / genetics
  • Polyarteritis Nodosa / pathology*
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrimidines / therapeutic use*
  • Pyrroles / therapeutic use*
  • Recurrence
  • STAT3 Transcription Factor / drug effects*
  • STAT3 Transcription Factor / genetics
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome

Substances

  • Piperidines
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Pyrroles
  • STAT3 Transcription Factor
  • STAT3 protein, human
  • tofacitinib