Sleep: Switching Off the Off-Switch

Curr Biol. 2016 Aug 22;26(16):R765-7. doi: 10.1016/j.cub.2016.06.059.

Abstract

What are the synaptic drives controlling the sleep-wake circuitry in the mammalian brain? In a new study it was found that GABAergic cells in posterior lateral hypothalamus inhibit sleep-promoting anterior hypothalamic cells to cause waking, whereas their inhibition augments sleep.

Publication types

  • Comment

MeSH terms

  • Animals
  • Brain
  • Hypothalamus
  • Sleep*
  • Wakefulness*