Fusion genes in solid tumors: the possibilities and the pitfalls

Expert Rev Mol Diagn. 2016 Sep;16(9):921-3. doi: 10.1080/14737159.2016.1220835. Epub 2016 Aug 23.
No abstract available

Keywords: FISH; Fusion gene; RT-PCR; chromosomal translocation; fusion protein; fusion transcript; immunohistochemistry; molecular pathology; next generation sequencing; targeted therapy.

Publication types

  • Editorial
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biomarkers, Tumor / genetics*
  • Biomarkers, Tumor / metabolism*
  • Humans
  • Neoplasms / genetics*
  • Neoplasms / metabolism*
  • Neoplasms / pathology
  • Oncogene Proteins, Fusion / genetics*
  • Oncogene Proteins, Fusion / metabolism*

Substances

  • Biomarkers, Tumor
  • Oncogene Proteins, Fusion