En Face Spectral-Domain Optical Coherence Tomography for the Diagnosis and Evaluation of Polypoidal Choroidal Vasculopathy

Ophthalmic Surg Lasers Imaging Retina. 2016 Aug 1;47(8):737-44. doi: 10.3928/23258160-20160808-07.

Abstract

Background and objective: To evaluate the diagnostic capability of en face spectral-domain optical coherence tomography (SD-OCT) in patients with polypoidal choroidal vasculopathy (PCV) diagnosed by indocyanine green angiography (ICGA).

Patients and methods: A retrospective, consecutive case series of 100 eyes diagnosed with PCV by ICGA were imaged with en face SD-OCT. Evaluation of the PCV complex on en face SD-OCT was performed on the ability to diagnose PCV by the characteristic configuration of the PCV complex and the extent and size of the PCV lesion.

Results: The PCV complex was better visualized on ICGA in 45 eyes, on en face SD-OCT in 44 eyes, and equally well in 11 eyes. The extent of the PCV complex was larger on en face SD-OCT in 65 eyes, larger on ICGA in 23 eyes, and equal in size in 12 eyes.

Conclusion: En face SD-OCT images the characteristic findings of PCV and provides a noninvasive way to diagnose and treat PCV when ICGA is not available. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:737-744.].

MeSH terms

  • Aged
  • Aged, 80 and over
  • Choroid / blood supply*
  • Choroid / pathology
  • Choroidal Neovascularization / diagnosis*
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Middle Aged
  • Ophthalmoscopy
  • Polyps / diagnosis*
  • Retrospective Studies
  • Tomography, Optical Coherence / methods*