Epidemiology and Etiology of Sarcomas

Jane Y C Hui

doi:10.1016/j.suc.2016.05.005

Epidemiology and Etiology of Sarcomas

Surg Clin North Am. 2016 Oct;96(5):901-14. doi: 10.1016/j.suc.2016.05.005.

Author

Jane Y C Hui¹

Affiliation

¹ Division of Surgical Oncology, Department of Surgery, University of Minnesota, 420 Delaware Street Southeast, Mayo Mail Code 195, Minneapolis, MN 55455, USA. Electronic address: jhui@umn.edu.

PMID: 27542634
DOI: 10.1016/j.suc.2016.05.005

Abstract

Sarcomas are rare malignancies of mesenchymal origin and are broadly divided into soft tissue sarcomas and bone sarcomas. The etiology of these tumors is largely unknown, and most sarcomas are sporadic. A small subset of sarcomas is associated with certain genetic syndromes and environmental factors. Ionizing radiation is the strongest environmental factor linked to sarcoma development.

Keywords: Epidemiology; Etiology; Li-Fraumeni; Radiation; Sarcoma.

Publication types

Review

MeSH terms

Diagnostic Imaging / methods*
Global Health
Humans
Incidence
Prevalence
Risk Assessment*
Risk Factors
Sarcoma / diagnosis*
Sarcoma / epidemiology*