Chemical Biology Interrogates Protein Arginine Phosphorylation

Cell Chem Biol. 2016 Aug 18;23(8):888-90. doi: 10.1016/j.chembiol.2016.08.003.

Abstract

Protein arginine phosphorylation has emerged as an important regulatory mechanism in Gram-positive bacteria, yet a couple of key mysteries remain. In this issue of Cell Chemical Biology, Fuhrmann et al. (2016) use activity-based probes to demonstrate that the protein arginine phosphatase YwlE is inactivated upon oxidative stress to unleash heat-shock gene expression.

Publication types

  • Comment

MeSH terms

  • Arginine*
  • Gram-Positive Bacteria
  • Oxidative Stress*
  • Phosphoprotein Phosphatases
  • Phosphorylation

Substances

  • Arginine
  • Phosphoprotein Phosphatases