Spinal metastases: multimodality imaging in diagnosis and stereotactic body radiation therapy planning

Future Oncol. 2017 Jan;13(1):77-91. doi: 10.2217/fon-2016-0238. Epub 2016 Aug 15.

Abstract

Due to increased effectiveness of cancer treatments and increasing survival rates, metastatic disease has become more frequent compared to the past, with the spine being the most common site of bony metastases. Diagnostic imaging is an integral part of screening, diagnosis and follow-up of spinal metastases. In this article, we review the principles of multimodality imaging for tumor detection with respect to their value for diagnosis and stereotactic body radiation therapy planning for spinal metastases. We will also review the current international consensus agreement for stereotactic body radiation therapy planning, and the role of imaging in achieving the best possible treatment plan.

Keywords: CT scan; MRI; PET; SBRT; SPECT; bone scan; metastasis; scintigraphy; spine.

Publication types

  • Review

MeSH terms

  • Humans
  • Multimodal Imaging / methods
  • Radiosurgery / methods
  • Radiotherapy Planning, Computer-Assisted
  • Spinal Neoplasms / diagnostic imaging*
  • Spinal Neoplasms / radiotherapy*
  • Spinal Neoplasms / secondary*
  • Treatment Outcome