Abstract
Multinucleate tumor cells were observed in a case of a retinal tumor suspected to be a retinoma (retinocytoma). On electron microscopy, these cells had characteristics of retinoblastoma. Similar cells were observed in an irradiated model of retinoblastoma grown in a nude mouse. We suggest that the presence of these cells indicates differentiation and/or regression of the tumor.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Calcinosis
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Cell Nucleus / ultrastructure*
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Cell Transformation, Neoplastic
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Child, Preschool
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Cytoplasm / ultrastructure
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Eye Neoplasms / ultrastructure*
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Female
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Humans
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Mice
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Mice, Nude
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Necrosis
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Neoplasm Transplantation
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Organelles / ultrastructure
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Retinoblastoma / ultrastructure*
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Skin Neoplasms / ultrastructure