Anti-K1 of the IgA class associated with Morganella morganii infection

Transfusion. 1989 Jul-Aug;29(6):549-51. doi: 10.1046/j.1537-2995.1989.29689318457.x.

Abstract

An anti-K1 alloantibody developed in a patient infected with Morganella morganii. The serologic behavior and response to dithiothreitol initially suggested that the alloantibody was an IgM. However, flow cytometry and the separation of immunoglobulin classes by serum chromatography revealed that the anti-K1 was constituted solely of IgA. These data suggest that bacteria-induced red cell antibodies might be of the IgA class.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Blood Group Antigens / immunology*
  • Blood Group Incompatibility / blood*
  • Blood Group Incompatibility / etiology
  • Blood Grouping and Crossmatching
  • Cell Separation
  • Coombs Test
  • Enterobacteriaceae Infections / blood*
  • Enterobacteriaceae Infections / complications
  • Humans
  • Immunoglobulin A / biosynthesis*
  • Isoantibodies / biosynthesis*
  • Kell Blood-Group System / immunology*
  • Male

Substances

  • Blood Group Antigens
  • Immunoglobulin A
  • Isoantibodies
  • Kell Blood-Group System