Abstract
Rhino-sinusal infections are serious diseases and possibly lethal. When they are invasive, we easily discuss apergilloses and mucormycoses. The confirmation of the diagnosis of mucormycosis need an extensive surgery for precise histopathological and mycological evaluation. The pathologist may be faced to other rare mycoses such as phaeohyphomycoses, which present different morphological features than mucormycoses and Aspergillus. Once the diagnosis is established, an appropriate antifungal treatment is quickly started. The aim of our work is to report two observations of phaeohyphomycoses, to describe their histopathological features, to discuss complementary diagnostic methods and to present the main differential diagnoses.
Keywords:
Alternaria; Aspergillose; Aspergillosis; Invasive; Mucormycose; Mucormycosis.
Copyright © 2016 Elsevier Masson SAS. All rights reserved.
MeSH terms
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Adult
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Alternaria / isolation & purification*
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Alternaria / ultrastructure
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Alternariosis / diagnosis
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Alternariosis / microbiology*
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Alternariosis / pathology
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Alternariosis / therapy
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Amphotericin B / administration & dosage
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Amphotericin B / therapeutic use
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Antifungal Agents / therapeutic use
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Combined Modality Therapy
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Debridement
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Diagnosis, Differential
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Early Diagnosis
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Fatal Outcome
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Female
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Humans
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Liposomes
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Mastoiditis / drug therapy
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Mastoiditis / microbiology
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Mastoiditis / surgery
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Phaeohyphomycosis / diagnosis
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Phaeohyphomycosis / microbiology*
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Phaeohyphomycosis / pathology
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Phaeohyphomycosis / therapy
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Postoperative Complications / etiology
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Retrospective Studies
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Rhinitis / diagnosis
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Rhinitis / microbiology*
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Rhinitis / pathology
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Rhinitis / therapy
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Shock, Septic / etiology
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Sinusitis / diagnosis
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Sinusitis / microbiology*
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Sinusitis / pathology
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Sinusitis / therapy
Substances
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Antifungal Agents
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Liposomes
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liposomal amphotericin B
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Amphotericin B