A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency
Gut
.
2017 Apr;66(4):756-758.
doi: 10.1136/gutjnl-2016-312398.
Epub 2016 Jul 29.
Authors
Soesma A Jankipersadsing
1
2
,
Fatemeh Hadizadeh
3
4
,
Marc Jan Bonder
2
,
Ettje F Tigchelaar
2
5
,
Patrick Deelen
2
6
,
Jingyuan Fu
1
2
,
Anna Andreasson
7
8
,
Lars Agreus
7
,
Susanna Walter
9
,
Cisca Wijmenga
2
,
Pirro Hysi
10
,
Mauro D'Amato
3
11
,
Alexandra Zhernakova
2
6
Affiliations
1
Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
2
Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
3
Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
4
School of Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran.
5
Top Institute Food and Nutrition, Wageningen, The Netherlands.
6
University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, The Netherlands.
7
Division of Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
8
Stress Research Institute, Stockholm University, Stockholm, Sweden.
9
Division of Gastroenterology, Institution of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
10
Department of Ophthalmology, King's College London, St Thomas' Hospital Campus, London, UK.
11
BioDonostia Health Research Institute San Sebastian and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
PMID:
27473416
PMCID:
PMC5529970
DOI:
10.1136/gutjnl-2016-312398
No abstract available
Keywords:
CYTOCHROME P450; GENETICS; INTESTINAL MOTILITY; META-ANALYSIS.
Publication types
Letter
Comment
MeSH terms
Cytochrome P-450 Enzyme System*
Inactivation, Metabolic*
Ion Channels
Substances
Ion Channels
Cytochrome P-450 Enzyme System