[Practical Use of the Levodopa Pump]

Fortschr Neurol Psychiatr. 2016 Jul;84(7):404-10. doi: 10.1055/s-0042-104503. Epub 2016 Jul 29.
[Article in German]

Abstract

Patients with advanced Parkinson's disease and motor complications undergoing optimized oral therapy can significantly benefit from continuous intrajejunal levodopa/carbidopa infusion applied by means of a medication pump. However, this requires a correctly positioned PEG-J tube and finely adjusted pump settings. Although this method is a routine procedure in specialist centers, no standard procedure has been defined up to now. For this reason, an expert recommendation regarding the practical application has been developed in order to standardize the procedure and facilitate patient access to this treatment option.

Publication types

  • Review

MeSH terms

  • Antiparkinson Agents / administration & dosage*
  • Antiparkinson Agents / adverse effects
  • Carbidopa / administration & dosage*
  • Carbidopa / adverse effects
  • Clinical Trials as Topic
  • Duodenum
  • Equipment Design
  • Gastrostomy
  • Humans
  • Infusion Pumps, Implantable*
  • Jejunum
  • Levodopa / administration & dosage*
  • Levodopa / adverse effects
  • Neurologic Examination / drug effects
  • Parkinson Disease / drug therapy*

Substances

  • Antiparkinson Agents
  • Levodopa
  • Carbidopa