Atypical central neurocytoma with metastatic craniospinal dissemination: a case report

Megha Nayyar; Mary Catherine Mayo; Mark Shiroishi; Deborah Commins; Charles Y Liu; John L Go; Paul E Kim; Chi-Shing Zee; Meng Law; Alexander Lerner

doi:10.1016/j.clinimag.2016.06.004

Atypical central neurocytoma with metastatic craniospinal dissemination: a case report

Clin Imaging. 2016 Nov-Dec;40(6):1108-1111. doi: 10.1016/j.clinimag.2016.06.004. Epub 2016 Jun 15.

Authors

Megha Nayyar¹, Mary Catherine Mayo², Mark Shiroishi³, Deborah Commins⁴, Charles Y Liu⁵, John L Go⁶, Paul E Kim⁷, Chi-Shing Zee⁸, Meng Law⁹, Alexander Lerner¹⁰

Affiliations

¹ Department of Radiology, Keck School of Medicine of the University of Southern California, 1500 San Pablo Street Second Floor Imaging, Los Angeles, CA 90033, USA. Electronic address: mnayyar@usc.edu.
² Department of Neurology, University of California, Los Angeles, 1801 Wilshire Boulevard, Los Angeles, CA 90409, USA. Electronic address: Katiemayo@gmail.com.
³ Department of Radiology, Keck School of Medicine of the University of Southern California, 1500 San Pablo Street Second Floor Imaging, Los Angeles, CA 90033, USA. Electronic address: mshioishi@gmail.com.
⁴ Department of Pathology, Keck School of Medicine of the University of Southern California, Hoffman Medical Research Center, 211 2011 Zonal Avenue, Los Angeles, CA 90089-9092, USA. Electronic address: commins@usc.edu.
⁵ Department of Neurosurgery, Keck School of Medicine of the University of Southern California, 1520 San Pablo St., Suite 3800, Los Angeles, CA 90033, USA. Electronic address: cliu@usc.edu.
⁶ Department of Radiology, Keck School of Medicine of the University of Southern California, 1500 San Pablo Street Second Floor Imaging, Los Angeles, CA 90033, USA. Electronic address: jlgo@usc.edu.
⁷ Department of Radiology, Keck School of Medicine of the University of Southern California, 1500 San Pablo Street Second Floor Imaging, Los Angeles, CA 90033, USA. Electronic address: pek@usc.edu.
⁸ Department of Radiology, Keck School of Medicine of the University of Southern California, 1500 San Pablo Street Second Floor Imaging, Los Angeles, CA 90033, USA. Electronic address: chishing@usc.edu.
⁹ Department of Radiology, Keck School of Medicine of the University of Southern California, 1500 San Pablo Street Second Floor Imaging, Los Angeles, CA 90033, USA. Electronic address: meng.law@usc.edu.
¹⁰ Department of Radiology, Keck School of Medicine of the University of Southern California, 1500 San Pablo Street Second Floor Imaging, Los Angeles, CA 90033, USA. Electronic address: alerner5@gmail.com.

PMID: 27450443
DOI: 10.1016/j.clinimag.2016.06.004

Abstract

Central neurocytomas comprise nearly half of adult intraventricular neoplasms. The median age of onset is 34 years. It is typically a low-grade neoplasm (World Health Organization grade II), although some cases of malignant neurocytomas have been described. We present a rare case of an atypical central neurocytoma with craniospinal dissemination, including both imaging and pathologic findings.

Keywords: Atypical central neurocytoma; Brain neoplasm; Craniospinal dissemination; Magnetic resonance imaging.

Published by Elsevier Inc.

Publication types

Case Reports

MeSH terms

Cerebral Ventricle Neoplasms / pathology*
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasm Invasiveness
Neurocytoma / pathology*
Spinal Cord Neoplasms / etiology*