Abstract
First-line docetaxel treatment for metastatic castration-sensitive prostate cancer is associated with higher rates of neutropenic fever compared with those with castration-resistant disease, and prophylactic granulocyte colony-stimulating factor should be considered in those harboring risk factors for developing neutropenia.
Copyright © 2016 European Association of Urology. Published by Elsevier B.V. All rights reserved.
MeSH terms
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Antineoplastic Agents / administration & dosage
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Chemotherapy-Induced Febrile Neutropenia* / diagnosis
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Chemotherapy-Induced Febrile Neutropenia* / etiology
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Chemotherapy-Induced Febrile Neutropenia* / prevention & control
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Docetaxel
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Humans
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Male
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Neoplasm Metastasis
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Neoplasm Staging
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Prostatic Neoplasms* / drug therapy
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Prostatic Neoplasms* / pathology
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Prostatic Neoplasms, Castration-Resistant* / drug therapy
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Prostatic Neoplasms, Castration-Resistant* / pathology
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Randomized Controlled Trials as Topic
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Taxoids* / administration & dosage
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Taxoids* / adverse effects
Substances
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Antineoplastic Agents
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Taxoids
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Docetaxel