Multiple eschars in scrub typhus: a case report

Trop Doct. 2017 Jan;47(1):67-69. doi: 10.1177/0049475516658400. Epub 2016 Jul 13.

Abstract

Eschar in scrub typhus aids in early diagnosis and institution of appropriate therapy; however, the eschar positivity rates vary greatly in endemic regions. Multiple eschars in scrub typhus are a rare presentation. Our patient presented with fever and multiple eschars and was empirically started on doxycycline. Nested polymerase chain reaction from all the four eschars and from EDTA blood were positive for 56-kDa type-specific antigen which is specific for Orientia tsutsugamushi The patient recovered completely after 7 days of antibiotic treatment. He was from an area where scrub typhus was not observed previously. An eschar in an acute febrile patient from the "tsutsugamushi triangle" is a valuable sign in scrub typhus diagnosis. A search for multiple eschars in scrub typhus must be made by clinicians.

Keywords: Doxycycline; Scrub typhus; multiple eschars; polymerase chain reaction (PCR).

Publication types

  • Case Reports

MeSH terms

  • Antigens, Bacterial / isolation & purification
  • Fever / etiology
  • Humans
  • Male
  • Orientia tsutsugamushi* / immunology
  • Orientia tsutsugamushi* / isolation & purification
  • Polymerase Chain Reaction
  • Scrub Typhus / complications
  • Scrub Typhus / diagnosis*
  • Skin / pathology*

Substances

  • Antigens, Bacterial