[Rectal mucosa metastasis in recurrent prostate cancer : (68)Ga-PSMA-PET/CT allows targeted salvage radiotherapy]

Urologe A. 2016 Aug;55(8):1086-8. doi: 10.1007/s00120-016-0169-3.
[Article in German]

Abstract

This article presents for the first time a case of rectal mucosa metastasis of recurrent prostate cancer that was diagnosed with (68)Ga-PSMA PET/CT. After histological confirmation, the patient was treated with salvage radiotherapy. This case report underlines the specificity and efficacy of PSMA-based PET imaging. In case of biochemical relapse, it can be used even at low PSA levels to detect prostate cancer metastases that might also be in atypical locations. Thus, (68)Ga-PSMA PET/CT may allow new options for salvage therapy.

Keywords: Metastasis; PSMA PET; Prostate cancer; Rectum; Salvage radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Edetic Acid / analogs & derivatives*
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Humans
  • Intestinal Mucosa / diagnostic imaging
  • Intestinal Mucosa / radiation effects
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnostic imaging*
  • Neoplasm Recurrence, Local / radiotherapy*
  • Oligopeptides*
  • Positron Emission Tomography Computed Tomography / methods*
  • Radiopharmaceuticals
  • Radiotherapy, Image-Guided / methods
  • Rectal Neoplasms / diagnostic imaging
  • Rectal Neoplasms / radiotherapy*
  • Rectal Neoplasms / secondary*
  • Salvage Therapy / methods
  • Treatment Outcome

Substances

  • Gallium Isotopes
  • Gallium Radioisotopes
  • Oligopeptides
  • Radiopharmaceuticals
  • gallium 68 PSMA-11
  • Edetic Acid