The obesity paradox suggests that overweight and obese patients of older age may have higher survival rates after stroke as compared to normalweight patients. However, the results need a cautious interpretation due to selection bias, treatment bias and different patients’ characteristics. Moreover, randomized studies that prove a benefit of weight reduction are still lacking. As obesity is an independet risk factor for stroke, weight reduction should still be recommended in overweight patients. Randomized-controlled studies are needed to prove the effect of weight reduction on morbidity and mortality after stroke.
Keywords: Adipositas; Hirnschlag; Mortalität; Thrombolyse; morbidité et mortalité post accident vasculaire cérébral; mortality; oberity; obésité; overweight; risque cardiovasculaire; stroke; surcharge pondérale; thrombolysis; Übergewicht.