Patients with hereditary fructose intolerance have normal erythrocyte aldolase activity

R Gitzelmann; B Steinmann; P Tuchschmid

doi:10.1016/0009-8981(89)90183-6

Patients with hereditary fructose intolerance have normal erythrocyte aldolase activity

Clin Chim Acta. 1989 May 15;181(2):163-6. doi: 10.1016/0009-8981(89)90183-6.

Authors

R Gitzelmann¹, B Steinmann, P Tuchschmid

Affiliation

¹ Department of Pediatrics, University of Zurich, Switzerland.

PMID: 2736779
DOI: 10.1016/0009-8981(89)90183-6

Abstract

Erythrocyte fructose 1,6-bisphosphate aldolase (EC 4.1.2.13) activity was measured in eight children and adults with hereditary fructose intolerance and found to be normal when compared with eleven healthy controls. Therefore, hereditary fructose intolerance cannot be diagnosed by assaying red blood cell aldolase.

MeSH terms

Adolescent
Adult
Child
Erythrocytes / enzymology*
Female
Fructose Intolerance / blood
Fructose Intolerance / enzymology*
Fructose Metabolism, Inborn Errors / enzymology*
Fructose-Bisphosphate Aldolase / blood*
Humans
Male

Substances

Fructose-Bisphosphate Aldolase