Persistence of Antibodies against Middle East Respiratory Syndrome Coronavirus

Emerg Infect Dis. 2016 Oct;22(10):1824-6. doi: 10.3201/eid2210.160706. Epub 2016 Oct 15.

Abstract

To determine how long antibodies against Middle East respiratory syndrome coronavirus persist, we measured long-term antibody responses among persons serologically positive or indeterminate after a 2012 outbreak in Jordan. Antibodies, including neutralizing antibodies, were detectable in 6 (86%) of 7 persons for at least 34 months after the outbreak.

Keywords: Jordan; MERS-CoV; Middle East respiratory syndrome; antibody; novel coronavirus; respiratory infections; serology; severe acute respiratory illness; viruses.

MeSH terms

  • Adult
  • Antibodies, Neutralizing / blood
  • Antibodies, Neutralizing / immunology
  • Antibodies, Viral / blood*
  • Antibodies, Viral / immunology
  • Coronavirus Infections / blood
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / immunology*
  • Disease Outbreaks
  • Female
  • Humans
  • Jordan / epidemiology
  • Male
  • Middle Aged
  • Middle East Respiratory Syndrome Coronavirus / immunology*
  • Time Factors

Substances

  • Antibodies, Neutralizing
  • Antibodies, Viral