Interim estimates of the effectiveness of influenza vaccination against influenza-associated hospitalization in children in Hong Kong, 2015-16

Influenza Other Respir Viruses. 2017 Jan;11(1):61-65. doi: 10.1111/irv.12399. Epub 2016 Oct 14.

Abstract

From 1 September 2015 through 31 January 2016, we enrolled 2068 children 6 months to 17 years of age admitted to hospital with a febrile acute respiratory infection in our test-negative study. Information on receipt of 2015-16 northern hemisphere inactivated influenza vaccination was elicited from parents or legal guardians. Using conditional logistic regression adjusting for age and matching on calendar time, we estimated influenza vaccine effectiveness against hospitalization with influenza A or B to be 79.2% (95% confidence interval: 42.0%-92.4%). Annual influenza vaccination should be more widely used in children in Hong Kong.

Keywords: effectiveness; hospitalization; influenza; interim; pediatrics; vaccine.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease / epidemiology
  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Hong Kong / epidemiology
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Influenza Vaccines / administration & dosage*
  • Influenza, Human / epidemiology*
  • Influenza, Human / prevention & control*
  • Influenza, Human / virology
  • Logistic Models
  • Male
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / prevention & control*
  • Respiratory Tract Infections / virology
  • Vaccination
  • Vaccine Potency*

Substances

  • Influenza Vaccines