Taking Advantage of Databases

Methods Mol Biol. 2016:1425:383-430. doi: 10.1007/978-1-4939-3609-0_17.

Abstract

Toxicity databases are a useful resource to support hazard and risk assessment. They are used to retrieve historical studies for compounds of interest and to support toxicity predictions where no data exists. Toxicity predictions are either based upon study results from similar chemicals or prediction models built from these databases.

Keywords: Expert review; Expert rule-based; In silico methods; QSAR models; Read across; Statistical-based; Structural alerts; Toxicity databases.

MeSH terms

  • Databases, Pharmaceutical*
  • Internet
  • Quantitative Structure-Activity Relationship
  • Toxicological Phenomena*
  • User-Computer Interface