Detection of CMV DNA in the perilymph of a 6-year-old boy with congenital cytomegalovirus infection

Ina Foulon; Oriane Soetens; Leen Vleurinck; Frans Gordts; Astrid Leus; Anne Naessens

Detection of CMV DNA in the perilymph of a 6-year-old boy with congenital cytomegalovirus infection

Ear Nose Throat J. 2016 Jun;95(6):234-9.

Authors

Ina Foulon¹, Oriane Soetens, Leen Vleurinck, Frans Gordts, Astrid Leus, Anne Naessens

Affiliation

¹ Department of Otolaryngology-Head and Neck Surgery, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium. ina.foulon@uzbrussel.be.

PMID: 27304443

Abstract

We present the case of a 6-year-old boy who received a cochlear implant for profound sensorineural hearing loss after being born with cytomegalovirus (CMV) infection. Even after 6 years, CMV DNA was still found in the perilymph of the cochlea. Our case shows that CMV DNA can be present in the cochlea years after congenital CMV infection, and it can explain why progressive and/or late-onset hearing loss occurs in these children.

Publication types

Case Reports

MeSH terms

Child
Cochlear Implantation
Cytomegalovirus / genetics*
Cytomegalovirus Infections / complications
Cytomegalovirus Infections / congenital*
Cytomegalovirus Infections / metabolism
DNA, Viral / metabolism*
Hearing Loss, Bilateral / etiology
Hearing Loss, Bilateral / surgery
Hearing Loss, Sensorineural / etiology
Hearing Loss, Sensorineural / surgery
Humans
Male
Perilymph / metabolism*
Perilymph / virology

Substances

DNA, Viral