No abstract available
Publication types
-
Letter
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Antineoplastic Agents / pharmacology
-
Antineoplastic Agents / therapeutic use*
-
Apoptosis / drug effects
-
Azetidines / pharmacology
-
Azetidines / therapeutic use
-
Carcinoma, Squamous Cell / drug therapy*
-
Cell Line, Tumor
-
Cellular Senescence / drug effects
-
Humans
-
Mitogen-Activated Protein Kinases / antagonists & inhibitors*
-
Molecular Targeted Therapy / methods
-
Piperidines / pharmacology
-
Piperidines / therapeutic use
-
Protein Kinase Inhibitors / pharmacology
-
Protein Kinase Inhibitors / therapeutic use*
-
Pyridones / pharmacology
-
Pyridones / therapeutic use
-
Pyrimidinones / pharmacology
-
Pyrimidinones / therapeutic use
-
Skin Neoplasms / drug therapy*
-
Xenograft Model Antitumor Assays
Substances
-
Antineoplastic Agents
-
Azetidines
-
Piperidines
-
Protein Kinase Inhibitors
-
Pyridones
-
Pyrimidinones
-
trametinib
-
Mitogen-Activated Protein Kinases
-
cobimetinib