Low Levels of Genetic Heterogeneity in Matched Lymph Node Metastases from Patients with Melanoma

J Invest Dermatol. 2016 Sep;136(9):1917-1920. doi: 10.1016/j.jid.2016.05.103. Epub 2016 Jun 2.

Authors

Milena Casula¹, Maria Colombino¹, Antonella Manca¹, Corrado Caracò², Gerardo Botti², Paolo A Ascierto², Amelia Lissia³, Antonio Cossu³, Giuseppe Palmieri⁴; Italian Melanoma Intergroup (IMI)

Collaborators

Italian Melanoma Intergroup (IMI):
Nicola Mozzillo, Panagiotis Paliogiannis, Paola Queirolo, Corrado Rubino, MariaCristina Sini, Ignazio Stanganelli, Francesco Tanda

Affiliations

¹ Istituto di Chimica Biomolecolare, CNR, Sassari, Italy.
² Istituto Nazionale Tumori, Napoli, Italy.
³ Dipartimento di Chirurgia, Microchirurgia e Scienze Mediche, Università di Sassari, Sassari, Italy.
⁴ Istituto di Chimica Biomolecolare, CNR, Sassari, Italy. Electronic address: gpalmieri@yahoo.com.

PMID: 27265006
DOI: 10.1016/j.jid.2016.05.103

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Female
GTP Phosphohydrolases / genetics
Genetic Heterogeneity*
Humans
Lymph Nodes / pathology*
Lymphatic Metastasis
Male
Melanoma / genetics*
Melanoma / pathology
Membrane Proteins / genetics
Middle Aged
Mutation
Polymorphism, Genetic
Proto-Oncogene Proteins B-raf / genetics
Sentinel Lymph Node Biopsy
Sequence Analysis, DNA
Skin Neoplasms / genetics*
Skin Neoplasms / pathology

Substances

Membrane Proteins
BRAF protein, human
Proto-Oncogene Proteins B-raf
GTP Phosphohydrolases
NRAS protein, human