Vascular Complications of Diabetes

Circ Res. 2016 May 27;118(11):1771-85. doi: 10.1161/CIRCRESAHA.115.306884.

Abstract

Over the last several decades, the global incidence and prevalence of diabetes mellitus has increased significantly. The raised incidence rate is projected to continue as greater numbers of persons adopt a Western lifestyle and diet. Patients with diabetes mellitus are at heightened risk of both adverse microvascular and cardiovascular events. Moreover, once cardiovascular disease develops, diabetes mellitus exacerbates progression and worsens outcomes. The medical management of patients with diabetes mellitus mandates comprehensive risk factor modification and antiplatelet therapy. Recent clinical trials of new medical therapies continue to inform the care of patients with diabetes mellitus to reduce both cardiovascular morbidity and mortality.

Keywords: atherosclerosis; cardiovascular disease; deep vein thrombosis; diabetes mellitus; risk factor.

Publication types

  • Review

MeSH terms

  • Atherosclerosis / drug therapy
  • Atherosclerosis / epidemiology*
  • Atherosclerosis / etiology
  • Clinical Trials as Topic
  • Diabetic Angiopathies / drug therapy
  • Diabetic Angiopathies / epidemiology*
  • Diabetic Angiopathies / pathology
  • Humans
  • Venous Thrombosis / drug therapy
  • Venous Thrombosis / epidemiology*
  • Venous Thrombosis / etiology