Health-related quality of life as a predictor of mortality in patients on peritoneal dialysis

Rev Lat Am Enfermagem. 2016:24:e2687. doi: 10.1590/1518-8345.0786.2687. Epub 2016 May 17.
[Article in English, Portuguese, Spanish]

Abstract

Objective: to characterize deaths that occurred, and the association between socio-demographic, clinical, laboratory variables and health-related quality of life and the outcome of death in patients on peritoneal dialysis, over a two year period after an initial assessment.

Method: observational, prospective population study with 82 patients on peritoneal dialysis. The instruments used for the first stage of data collection were the mini-mental state examination, a sociodemographic, economic, clinical and laboratory questionnaire and the Kidney Disease and Quality of Life-Short Form. After two years, data for characterization and occurrence of death in the period were collected. The relative risk of death outcome was calculated through statistical analysis; the risk of death was estimated by the survival Kaplan-Meier curve, and determined predictors of death by the Cox Proportional Hazards Model.

Results: of the 82 original participants, 23 had as an outcome death within two years. The increased risk for the outcome of death was associated with a lower mean score of health-related quality of life in the physical functioning domain.

Conclusion: the worst health-related quality of life in the physical functioning domain, could be considered a predictor of death.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Health Status
  • Humans
  • Kaplan-Meier Estimate
  • Kidney Diseases / mortality
  • Kidney Diseases / therapy
  • Peritoneal Dialysis / mortality*
  • Proportional Hazards Models
  • Prospective Studies
  • Quality of Life*
  • Surveys and Questionnaires