Liposomes containing an ASP49-phospholipase A2 from Bothrops jararacussu snake venom as experimental therapy against cutaneous leishmaniasis

Int Immunopharmacol. 2016 Jul:36:225-231. doi: 10.1016/j.intimp.2016.04.025. Epub 2016 May 9.
No abstract available

Keywords: Asp49-phospholipase A(2); Bothrops jararacussu; Cutaneous leishmaniasis; Liposomes; Treatment.

MeSH terms

  • Animals
  • Bothrops / metabolism*
  • Cell Line
  • Cell Survival
  • Crotalid Venoms / metabolism*
  • Drug Delivery Systems
  • Leishmania / physiology*
  • Leishmaniasis, Cutaneous / drug therapy*
  • Liposomes / metabolism
  • Liposomes / pharmacology*
  • Macrophages / drug effects*
  • Macrophages / parasitology
  • Macrophages / physiology
  • Mice
  • Nitrites / metabolism
  • Phospholipases A2 / metabolism
  • Phospholipases A2 / pharmacology*
  • Tumor Necrosis Factor-alpha / metabolism

Substances

  • Crotalid Venoms
  • Liposomes
  • Nitrites
  • Tumor Necrosis Factor-alpha
  • Phospholipases A2