High Prevalence of Infectious Diseases and Drug-Resistant Microorganisms in Asylum Seekers Admitted to Hospital; No Carbapenemase Producing Enterobacteriaceae until September 2015

PLoS One. 2016 May 4;11(5):e0154791. doi: 10.1371/journal.pone.0154791. eCollection 2016.

Abstract

Introduction: The current refugee crisis emphasizes the need for information on infectious diseases and resistant microorganisms in asylum seekers with possible consequences for public health and infection control.

Methods: We collected data from asylum seekers admitted to our university hospital or who presented at the Emergency Department (n = 273). We collected general and demographic characteristics including country of origin, the reason of presentation, and the screening results of multi-drug resistant organisms.

Results: 67% of the patients were male with a median age of the study group of 24 years (IQR 15-33); 48% of the patients had an infectious disease-predominantly malaria with P. vivax or tuberculosis. Patients also reported with diseases which are less common-e.g. leishmaniasis, or even conditions rarely diagnosed in Europe-e.g. louse borne relapsing fever. A carriage rate of 31% for multi-drug resistant microorganisms (MDRO) was observed, with ESBL-expressing E.coli (n = 20) being the most common MDRO. No carriage of Carbapenemase Producing Enterobacteriaceae was found.

Conclusion: The current refugee crisis in Europe challenges hospitals to quickly identify and respond to communicable diseases and the carriage of MDRO. A rapid response is necessary to optimize the treatment of infectious diseases amongst asylum seekers to maximize infection control.

MeSH terms

  • Adolescent
  • Adult
  • Bacterial Proteins / metabolism*
  • Communicable Diseases / epidemiology*
  • Communicable Diseases / microbiology*
  • Drug Resistance, Bacterial
  • Enterobacteriaceae / isolation & purification*
  • Enterobacteriaceae / metabolism*
  • Europe / epidemiology
  • Female
  • Hospitalization
  • Hospitals, University
  • Humans
  • Male
  • Prevalence
  • Public Health / methods
  • Refugees
  • Young Adult
  • beta-Lactamases / metabolism*

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase

Grants and funding

The authors have no support or funding to report.