Compelling Relationship of CYP3A Induction to Levels of the Putative Biomarker 4β-Hydroxycholesterol and Changes in Midazolam Exposure
Clin Pharmacol Drug Dev
.
2016 Jul;5(4):245-9.
doi: 10.1002/cpdd.265.
Authors
James B Mangold
1
,
Fan Wu
1
,
Sam Rebello
1
Affiliation
1
Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
PMID:
27138133
DOI:
10.1002/cpdd.265
No abstract available
MeSH terms
Biomarkers
Cytochrome P-450 CYP3A
Hydroxycholesterols / analysis*
Midazolam
Substances
Biomarkers
Hydroxycholesterols
cholest-5-ene-3,4-diol
Cytochrome P-450 CYP3A
Midazolam