Immunohistochemistry for NF2, LATS1/2, and YAP/TAZ Fails to Separate Benign From Malignant Mesothelial Proliferations

Arch Pathol Lab Med. 2016 May;140(5):391. doi: 10.5858/arpa.2015-0508-LE.
No abstract available

Publication types

  • Letter
  • Validation Study

MeSH terms

  • Active Transport, Cell Nucleus
  • Adaptor Proteins, Signal Transducing / metabolism*
  • Amino Acid Substitution
  • Antibody Specificity
  • Biomarkers, Tumor / metabolism
  • Cell Nucleus / metabolism
  • Cell Nucleus / pathology
  • Cell Proliferation
  • Diagnosis, Differential
  • Humans
  • Immunohistochemistry
  • Intracellular Signaling Peptides and Proteins / metabolism*
  • Mesothelioma / diagnosis
  • Mesothelioma / metabolism*
  • Mesothelioma / pathology
  • Mutation*
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism*
  • Neurofibromin 2 / genetics
  • Neurofibromin 2 / metabolism*
  • Phosphoproteins / metabolism*
  • Protein Serine-Threonine Kinases / genetics
  • Protein Serine-Threonine Kinases / metabolism*
  • Tissue Array Analysis
  • Trans-Activators
  • Transcription Factors
  • Transcriptional Coactivator with PDZ-Binding Motif Proteins
  • Tumor Suppressor Proteins / metabolism*
  • YAP-Signaling Proteins

Substances

  • Adaptor Proteins, Signal Transducing
  • Biomarkers, Tumor
  • Intracellular Signaling Peptides and Proteins
  • Neoplasm Proteins
  • Neurofibromin 2
  • Phosphoproteins
  • Trans-Activators
  • Transcription Factors
  • Transcriptional Coactivator with PDZ-Binding Motif Proteins
  • Tumor Suppressor Proteins
  • WWTR1 protein, human
  • YAP-Signaling Proteins
  • YAP1 protein, human
  • LATS1 protein, human
  • LATS2 protein, human
  • Protein Serine-Threonine Kinases