Precision medicine and oncology: an overview of the opportunities presented by next-generation sequencing and big data and the challenges posed to conventional drug development and regulatory approval pathways

Ann Oncol. 2016 Aug;27(8):1644-6. doi: 10.1093/annonc/mdw165. Epub 2016 Apr 26.

Authors

M Doherty¹, T Metcalfe², E Guardino³, E Peters³, L Ramage²

Affiliations

¹ Genentech, Inc., South San Francisco, USA doherty.michael@gene.com.
² F. Hoffmann-La Roche, Basel, Switzerland.
³ Genentech, Inc., South San Francisco, USA.

PMID: 27117532
DOI: 10.1093/annonc/mdw165

No abstract available

Publication types

Editorial

MeSH terms

Data Interpretation, Statistical
Drug Approval / methods*
Drug Discovery / methods*
Drug Discovery / trends
High-Throughput Nucleotide Sequencing / methods*
High-Throughput Nucleotide Sequencing / trends
Humans
Medical Oncology / methods*
Medical Oncology / trends
Neoplasms / diagnosis
Neoplasms / drug therapy
Neoplasms / genetics*
Precision Medicine / methods*
Precision Medicine / trends