Multimorbidity in Older Adults with Aortic Stenosis

Abstract

Aortic stenosis is a disease of older adults; many have associated comorbidities. With the aging of the population and the emergence of transcatheter aortic valve replacement as a treatment, clinicians will increasingly be confronted with aortic stenosis and multimorbidity, making the evaluation, management, and treatment of aortic stenosis more complex. To optimize patient-centered clinical outcomes, new treatment paradigms are needed that recognize the import and influence of multimorbidity on patients with aortic stenosis. The authors review the prevalence of medical and aging-related comorbidities in patients with aortic stenosis, their impact on outcomes, and discuss how they influence management and treatment decisions.

Keywords: Aortic stenosis; Cardiac surgery; Cardiovascular disease; Comorbidity; Frailty; Geriatrics; Multimorbidity; Transcatheter aortic valve replacement.