Severe Sepsis and Septic Shock Associated with Chikungunya Virus Infection, Guadeloupe, 2014

Emerg Infect Dis. 2016 May;22(5):891-4. doi: 10.3201/eid2205.151449.

Abstract

During a 2014 outbreak, 450 patients with confirmed chikungunya virus infection were admitted to the University Hospital of Pointe-à-Pitre, Guadeloupe. Of these, 110 were nonpregnant adults; 42 had severe disease, and of those, 25 had severe sepsis or septic shock and 12 died. Severe sepsis may be a rare complication of chikungunya virus infection.

Keywords: CHIKV; French West Indies; Guadeloupe; chikungunya; septic shock; severe sepsis; vector-borne infections; viruses.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Chikungunya Fever / diagnosis
  • Chikungunya Fever / epidemiology*
  • Chikungunya virus*
  • Child
  • Child, Preschool
  • Comorbidity
  • Disease Outbreaks
  • Female
  • Guadeloupe / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Patient Outcome Assessment
  • Pregnancy
  • Sepsis / epidemiology*
  • Sepsis / virology*
  • Shock, Septic / diagnosis
  • Shock, Septic / epidemiology*
  • Shock, Septic / virology*
  • Young Adult