Mapping the Epidemiology of Kaposi Sarcoma and Non-Hodgkin Lymphoma Among Children in Sub-Saharan Africa: A Review

Pediatr Blood Cancer. 2016 Aug;63(8):1325-31. doi: 10.1002/pbc.26021. Epub 2016 Apr 15.

Abstract

Children with human immunodeficiency virus (HIV) have an increased risk of developing Kaposi Sarcoma (KS) and non-Hodgkin lymphoma (NHL) compared to HIV-negative children. We compiled currently published epidemiologic data on KS and NHL among children in sub-Saharan Africa (SSA). Among countries with available data, the median incidence of KS was 2.05/100,000 in the general pediatric population and 67.35/100,000 among HIV-infected children. The median incidence of NHL was 1.98/100,000 among the general pediatric population, while data on NHL incidence among HIV-infected children were lacking. Larger regional studies are needed to better address the dearth of epidemiologic information on pediatric KS and NHL in SSA.

Keywords: Africa; Kaposi sarcoma; epidemiology; non-Hodgkin lymphoma; pediatric.

Publication types

  • Review

MeSH terms

  • Africa South of the Sahara / epidemiology
  • Child
  • HIV Infections / epidemiology*
  • Herpesvirus 4, Human
  • Herpesvirus 8, Human
  • Humans
  • Lymphoma, Non-Hodgkin / epidemiology*
  • Sarcoma, Kaposi / epidemiology*