Direct oxidative lactonization of alkenoic acids mediated solely by NaIO4: beyond a simple oxidant

Chem Commun (Camb). 2016 May 4;52(36):6193-6. doi: 10.1039/c6cc02246d. Epub 2016 Apr 14.

Abstract

Triflic acid-catalyzed direct oxidative lactonization of alkenoic acids mediated solely by NaIO4 without halogen salts is described. Sodium periodate works not only as an oxidant, but also as an active reagent and directly mediates the lactonization. A new cheap, green, and practical oxidative lactonization approach has been developed using NaIO4 as the sole reagent.

Publication types

  • Research Support, Non-U.S. Gov't