Programming Molecular Association and Viscoelastic Behavior in Protein Networks

Adv Mater. 2016 Jun;28(23):4651-7. doi: 10.1002/adma.201506216. Epub 2016 Apr 9.

Abstract

A set of recombinant artificial proteins that can be cross-linked, by either covalent bonds or association of helical domains or both, is described. The designed proteins can be used to construct molecular networks in which the mechanism of crosslinking determines the time-dependent responses to mechanical deformation.

Keywords: artificial proteins; hydrogels; viscoelastic networks.

MeSH terms

  • Elasticity*
  • Hydrogels / chemistry
  • Protein Domains
  • Recombinant Proteins / chemistry*
  • Rheology
  • Time Factors
  • Viscosity

Substances

  • Hydrogels
  • Recombinant Proteins