Complete Genome Sequence of Streptococcus mitis Strain SVGS_061 Isolated from a Neutropenic Patient with Viridans Group Streptococcal Shock Syndrome

Varduhi Petrosyan; Michael Holder; Nadim J Ajami; Joseph F Petrosino; Pranoti Sahasrabhojane; Erika J Thompson; Awdhesh Kalia; Samuel A Shelburne

doi:10.1128/genomeA.00259-16

Complete Genome Sequence of Streptococcus mitis Strain SVGS_061 Isolated from a Neutropenic Patient with Viridans Group Streptococcal Shock Syndrome

Genome Announc. 2016 Apr 7;4(2):e00259-16. doi: 10.1128/genomeA.00259-16.

Authors

Varduhi Petrosyan¹, Michael Holder², Nadim J Ajami², Joseph F Petrosino², Pranoti Sahasrabhojane³, Erika J Thompson⁴, Awdhesh Kalia¹, Samuel A Shelburne⁵

Affiliations

¹ Graduate Program in Diagnostic Genetics, School of Health Professions, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
² The Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
³ Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
⁴ Graduate Program in Diagnostic Genetics, School of Health Professions, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA Sequencing and Microarray Facility, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
⁵ Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA sshelburne@mdanderson.org.

Abstract

Streptococcus mitisfrequently causes invasive infections in neutropenic cancer patients, with a subset of patients developing viridans group streptococcal (VGS) shock syndrome. We report here the first complete genome sequence ofS. mitisstrain SVGS_061, which caused VGS shock syndrome, to help elucidate the pathogenesis of severe VGS infection.

Abstract

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