Keywords: MEN, multiple endocrine neoplasia; PEN, palisaded and encapsulated neuroma; PTEN, phosphatase and tensin homolog; PTEN-tumor hamartoma syndrome; PTHS, PTEN tumor-hamartoma syndrome; genodermatoses; multiple endocrine neoplasia 2B; neuroma; palisaded and encapsulated neuroma; peripheral nerve sheath tumor.