Laser-induced thermal occlusion of berry aneurysms: initial experimental results

Radiology. 1989 May;171(2):471-4. doi: 10.1148/radiology.171.2.2704814.

Abstract

An intravascular laser-catheter technique was used to occlude 12 experimental berry aneurysms, ranging in size from 4 X 3 mm to 8 X 6 mm (length X width), while the patency of adjacent arteries was preserved. A small steel cap on the end of an optical fiber was fluoroscopically positioned within the aneurysm. The cap was rapidly heated by the optical transmission of laser energy. This produced a thermal tissue reaction within the aneurysm, resulting in its occlusion. After treatment, the steel cap was detached atraumatically from the fiber and left as a permanent implant within the occluded aneurysm. This method has an advantage over the use of a bare-ended intravascular optical fiber because the steel cap provides a uniform distribution of thermal energy, thereby reducing the risk of unexpected perforation during treatment. The radiologic and histologic results of using this laser-catheter system were evaluated 1-21 weeks after treatment.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Carotid Artery Diseases / therapy*
  • Catheterization / instrumentation
  • Embolization, Therapeutic / methods*
  • Fiber Optic Technology / instrumentation
  • Intracranial Aneurysm / therapy*
  • Laser Therapy*
  • Optical Fibers
  • Prostheses and Implants
  • Rabbits