The ontogeny of the cortical language network

Nat Rev Neurosci. 2016 May;17(5):323-32. doi: 10.1038/nrn.2016.23. Epub 2016 Apr 4.

Abstract

Language-processing functions follow heterogeneous developmental trajectories. The human embryo can already distinguish vowels in utero, but grammatical complexity is usually not fully mastered until at least 7 years of age. Examining the current literature, we propose that the ontogeny of the cortical language network can be roughly subdivided into two main developmental stages. In the first stage extending over the first 3 years of life, the infant rapidly acquires bottom-up processing capacities, which are primarily implemented bilaterally in the temporal cortices. In the second stage continuing into adolescence, top-down processes emerge gradually with the increasing functional selectivity and structural connectivity of the left inferior frontal cortex.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain Mapping / methods
  • Child
  • Child Development / physiology
  • Child, Preschool
  • Humans
  • Language*
  • Nerve Net / growth & development*
  • Neural Pathways / growth & development
  • Prefrontal Cortex / growth & development*