Whole-body radiofrequency coil for (31) P MRSI at 7 T

NMR Biomed. 2016 Jun;29(6):709-20. doi: 10.1002/nbm.3517. Epub 2016 Apr 1.

Abstract

Widespread use of ultrahigh-field (31) P MRSI in clinical studies is hindered by the limited field of view and non-uniform radiofrequency (RF) field obtained from surface transceivers. The non-uniform RF field necessitates the use of high specific absorption rate (SAR)-demanding adiabatic RF pulses, limiting the signal-to-noise ratio (SNR) per unit of time. Here, we demonstrate the feasibility of using a body-sized volume RF coil at 7 T, which enables uniform excitation and ultrafast power calibration by pick-up probes. The performance of the body coil is examined by bench tests, and phantom and in vivo measurements in a 7-T MRI scanner. The accuracy of power calibration with pick-up probes is analyzed at a clinical 3-T MR system with a close to identical (1) H body coil integrated at the MR system. Finally, we demonstrate high-quality three-dimensional (31) P MRSI of the human body at 7 T within 5 min of data acquisition that includes RF power calibration. Copyright © 2016 John Wiley & Sons, Ltd.

Keywords: 31P; 7 T; MRSI; RF coil.

Publication types

  • Evaluation Study

MeSH terms

  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Magnetic Resonance Imaging / instrumentation*
  • Magnetic Resonance Spectroscopy / instrumentation*
  • Magnetics / instrumentation*
  • Molecular Imaging / instrumentation*
  • Phosphorus Compounds / metabolism*
  • Phosphorus Isotopes / pharmacokinetics*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Transducers
  • Whole Body Imaging / instrumentation*

Substances

  • Phosphorus Compounds
  • Phosphorus Isotopes