POEM, the Prototypical "New NOTES" Procedure and First Successful NOTES Procedure

Gastrointest Endosc Clin N Am. 2016 Apr;26(2):237-255. doi: 10.1016/j.giec.2015.12.002.

Abstract

Peroral endoscopic myotomy (POEM) was first performed in 2008 as a novel treatment of achalasia. It is now performed globally, demonstrating the evolution of the first successful natural orifice transluminal endoscopic surgery (NOTES) procedure. There is extensive data demonstrating the safety and efficacy of POEM, and now long-term data has emerged demonstrating that the efficacy is durable. POEM is also being used to successfully treat diffuse esophageal spasm (DES) and jackhammer esophagus. With jackhammer esophagus and DES, inclusion of the lower esophageal sphincter in the myotomy minimizes the risk of symptom development from iatrogenic ineffective esophageal motility.

Keywords: Achalasia; Diffuse esophageal spasm; Hypercontractile esophagus; Jackhammer esophagus; Natural orifice transluminal endoscopic surgery (NOTES); Peroral endoscopic myotomy (POEM).

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Esophageal Achalasia / surgery*
  • Esophageal Sphincter, Lower / surgery
  • Esophagoscopy / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mouth / surgery
  • Natural Orifice Endoscopic Surgery / methods*
  • Young Adult