MaxReport: An Enhanced Proteomic Result Reporting Tool for MaxQuant

PLoS One. 2016 Mar 22;11(3):e0152067. doi: 10.1371/journal.pone.0152067. eCollection 2016.

Abstract

MaxQuant is a proteomic software widely used for large-scale tandem mass spectrometry data. We have designed and developed an enhanced result reporting tool for MaxQuant, named as MaxReport. This tool can optimize the results of MaxQuant and provide additional functions for result interpretation. MaxReport can generate report tables for protein N-terminal modifications. It also supports isobaric labelling based relative quantification at the protein, peptide or site level. To obtain an overview of the results, MaxReport performs general descriptive statistical analyses for both identification and quantification results. The output results of MaxReport are well organized and therefore helpful for proteomic users to better understand and share their data. The script of MaxReport, which is freely available at http://websdoor.net/bioinfo/maxreport/, is developed using Python code and is compatible across multiple systems including Windows and Linux.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Protein
  • Peptides / metabolism
  • Proteome / metabolism*
  • Proteomics / methods*
  • Software
  • Tandem Mass Spectrometry / methods

Substances

  • Peptides
  • Proteome

Grants and funding

The work was supported by the National Natural Science Foundation of China (no. 31400727). FW received the funding. The work was also supported by the China Postdoctoral Science Foundation (no. 2015M581836). TZ received the funding. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.