Primary squamous cell carcinoma (SCC) is extremely rare in the seminal vesicle. A 26-year-old male patient presented with complaints of difficulty in urination for 10 years and gross hematuria for 7 months. Ultrasonography and computed tomography imaging demonstrated a large mixed solid/cystic mass lesions in the rectovesical pouch. The mass was completely resected with the open approach and was verified as a primary SCC of the seminal vesicle by post-surgical histopathological examination. Pelvic metastases were detected 28 months after the surgery. This is the third reported case of primary SCC of the seminal vesicle, and the first one in a young patient. Early diagnosis and treatment are crucial for primary SCC of the seminal vesicle.
Keywords: hematuria; seminal vesicle carcinoma; squamous cell carcinoma.