[Antifungal effects in vitro of jasmon and some similar compounds. Structure-activity relationship]

Ann Pharm Fr. 1989;47(3):157-61.
[Article in French]

Abstract

The antimycotic activity in vitro of jasmon and 6 closely related substances has been tested against four different dermatophytes, Candida albicans, Pityrosporum ovale and Aspergillus fumigatus. Jasmon had the highest activity. Among the other substances tested only thiazolidines with a carbonyl function developed antifungal properties against dermatophytes. 2,4 thiazolidinedione at 450 ppm inhibits the growth of Trichophyton rubrum.

MeSH terms

  • Antifungal Agents / pharmacology*
  • Aspergillus fumigatus / drug effects
  • Candida albicans / drug effects
  • In Vitro Techniques
  • Malassezia / drug effects
  • Microbial Sensitivity Tests
  • Microsporum / drug effects
  • Plants, Medicinal / analysis
  • Structure-Activity Relationship
  • Trichophyton / drug effects

Substances

  • Antifungal Agents