Melanoma-Directed Activation of Apoptosis Using a Bispecific Antibody Directed at MCSP and TRAIL Receptor-2/Death Receptor-5

J Invest Dermatol. 2016 Feb;136(2):541-544. doi: 10.1016/j.jid.2015.11.009. Epub 2015 Dec 2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis / drug effects
  • Apoptosis / immunology*
  • Binding Sites
  • Humans
  • Melanoma / drug therapy
  • Melanoma / immunology
  • Melanoma / pathology
  • Mitochondrial Proteins / immunology*
  • Mitochondrial Proteins / metabolism
  • Molecular Targeted Therapy / methods
  • Receptors, TNF-Related Apoptosis-Inducing Ligand / immunology*
  • Receptors, TNF-Related Apoptosis-Inducing Ligand / metabolism
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / immunology
  • Skin Neoplasms / pathology
  • Statistics, Nonparametric
  • Tumor Cells, Cultured / immunology
  • Tumor Cells, Cultured / metabolism

Substances

  • Mitochondrial Proteins
  • Receptors, TNF-Related Apoptosis-Inducing Ligand
  • SMCP protein, human