Reductive debromination of 1,2-dibromides with anisidines

Tetrahedron Lett. 2016 Jan 20;57(3):285-287. doi: 10.1016/j.tetlet.2015.11.106.

Abstract

vic -Dibromides containing the α-bromocarbonyl or α-bromoaromatic moieties were reductively debrominated to furnish alkenes in high yield. o- and m-Anisidines but not p-anisidine were found to be effective debrominating agents. The reductive debrominations were found to be trans-stereospecific.

Keywords: Anisidine; Debromination; Redution; vic-Dibromides.