Papillomavirus in yaks: the isolates of bovine papillomavirus type 1 have a high possibility of belonging to a novel type

J Vet Med Sci. 2016 Jul 1;78(6):1059-61. doi: 10.1292/jvms.15-0479. Epub 2016 Feb 27.

Abstract

Although papillomaviruses (PVs) have been widely reported in vertebrates, there have been only a few PV reports in yaks (Bos grunniens). In 2012, Bam et al. reported bovine papillomavirus type 1 (BPV-1) and BPV-2 associated with cutaneous papillomatosis in yaks, which provided genomic and pathology information for yak PVs. However, nucleotide identity and phylogenic analyses revealed that there are two isolates with a high possibility of belonging to a novel type that is not BPV-1. The argument was thought to be caused by type-specific primers. Our analysis showed that BPV-1 type-specific primers can detect not only BPV-1 but also other PVs. It suggests that identification results using type-specific primers should be confirmed with more robust methods in molecular epidemiological studies.

MeSH terms

  • Animals
  • Bovine papillomavirus 1 / genetics
  • Bovine papillomavirus 1 / isolation & purification
  • Cattle / virology*
  • Papillomaviridae / genetics
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / veterinary*
  • Papillomavirus Infections / virology
  • Phylogeny