SKA2 methylation predicts reduced cortical thickness in prefrontal cortex

N Sadeh; J M Spielberg; M W Logue; E J Wolf; A K Smith; J Lusk; J P Hayes; E Sperbeck; W P Milberg; R E McGlinchey; D H Salat; W C Carter; A Stone; S A Schichman; D E Humphries; M W Miller

doi:10.1038/mp.2016.10

SKA2 methylation predicts reduced cortical thickness in prefrontal cortex

Mol Psychiatry. 2016 Mar;21(3):299. doi: 10.1038/mp.2016.10.

Authors

N Sadeh^{1

2}, J M Spielberg^{2

3}, M W Logue^{4

5

6}, E J Wolf^{1

2}, A K Smith⁷, J Lusk¹, J P Hayes^{1

2

3}, E Sperbeck¹, W P Milberg^{8

9}, R E McGlinchey^{8

9}, D H Salat^{3

10}, W C Carter¹¹, A Stone¹¹, S A Schichman¹¹, D E Humphries¹², M W Miller^{1

2}

Affiliations

¹ National Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, USA.
² Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA.
³ Neuroimaging Research for Veterans Center, VA Boston Healthcare System, Boston, MA, USA.
⁴ Research Service, VA Boston Healthcare System, Boston, MA, USA.
⁵ Department of Biomedical Genetics, Boston University School of Medicine, Boston, MA, USA.
⁶ Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
⁷ Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
⁸ Translational Research Center for TBI and Stress Disorders and Geriatric Research, Educational and Clinical Center, VA Boston Healthcare System, Boston, MA, USA.
⁹ Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
¹⁰ Department of Radiology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
¹¹ Pharmacogenomics Analysis Laboratory, Research Service, Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.
¹² Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston, MA, USA.

PMID: 26887336
DOI: 10.1038/mp.2016.10

No abstract available

MeSH terms

Brain Mapping
Chromosomal Proteins, Non-Histone / genetics*
DNA Methylation / genetics*
Humans
Predictive Value of Tests
Prefrontal Cortex / pathology*

Substances

Chromosomal Proteins, Non-Histone
SKA2 protein, human