[Metastatic bronchial carcinoid tumors]

Rev Pneumol Clin. 2016 Feb;72(1):41-8. doi: 10.1016/j.pneumo.2015.12.002. Epub 2016 Jan 30.
[Article in French]

Abstract

Bronchial carcinoids are uncommon pulmonary neoplasms and represent 1 to 2 % of all lung tumors. In early stage of disease, the mainstay and only curative treatment is surgery. Bronchial carcinoids are generally regarded as low-grade carcinomas and metastatic dissemination is unusual. The management of the metastatic stage is not currently standardized due to a lack of relevant studies. As bronchial carcinoids and in particular their metastatic forms are rare, we apply treatment strategies that have been evaluated in gastrointestinal and pancreatic neuroendocrine tumors. However, bronchial carcinoids have their own characteristic. A specific therapeutic feature of these metastatic tumors is that they require a dual approach: both anti-secretory for the carcinoid syndrome, and anti-tumoral.

Keywords: Anatomopathologie; Anatomopathology; Bronchial carcinoids; Carcinoid syndrome; Carcinoïdes bronchiques; Chemotherapy; Chimiothérapie; Metastatic stage; Stade métastatique; Syndrome carcinoïde; Traitements; Treatment.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Biomarkers, Tumor / blood
  • Bronchial Neoplasms* / epidemiology
  • Bronchial Neoplasms* / pathology
  • Bronchial Neoplasms* / therapy
  • Carcinoid Tumor* / epidemiology
  • Carcinoid Tumor* / pathology
  • Carcinoid Tumor* / therapy
  • Diagnostic Imaging / methods
  • Humans
  • Neoplasm Metastasis

Substances

  • Biomarkers, Tumor